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first_imgSky Sports has announced 25 of its 64 matches will be free-to-air on its Pick channel, while the BBC has the rights to screen four games on terrestrial TV.It will be the first time the BBC has shown any live English top-flight action since 1988. Amazon will make its four Premier League matches in the remainder of the 2019/20 season free-to-air as broadcasters prepare for the return of the English top-flight.The Premier League is set to resume behind closed doors on June 17 after being suspended since March due to the coronavirus.All 92 remaining fixtures will be televised live and Amazon has a small package of games. Topics :center_img Unlike earlier this season, fans will not need a Prime membership to watch fixtures on the online platform.”Like the rest of the country, we are excited to see the Premier League return to action,” said Alex Green, managing director of Prime Video Sport Europe.”We will be making all four of Amazon Prime Video’s additional fixtures in the 2019-20 season available free of charge. Fans will not need a Prime membership to view the games on Prime Video.”The online streaming service entered the competitive Premier League live rights market in 2018, changing the landscape of British sports broadcasting.last_img read more

first_imgAcute leukaemia has a high relapse rateScientists are working on a way to stop one of the most aggressive forms of acute leukaemia, MLL, returning after a patient has received treatment.Recurrence of the blood cancer caused by rogue leukaemic stem cells is a major problem for doctors.But a team at King’s College London, working on mice, have raised hopes of a solution.They describe in the journal Cell Stem Cell how they eliminated the stem cells by suppressing two key proteins.It is hoped the work, funded by Cancer Research UK and Leukaemia Lymphoma Research, will lead to new treatments which will enable complete remission for patients with a form of acute leukaemia.Cancer stem cells appear to be more resistant than other leukaemia cells to standard treatments, such as radiotherapy and chemotherapy.So even after treatment appears to have been initially successful, they can remain to trigger a new round of disease, which often reappears in a more aggressive form.More than 50% of acute leukaemia patients will relapse and survival is poor, with fewer than half living for five years.The King’s team looked at leukaemic stem cells found in a type of acute leukaemia involving mutations in a gene called MLL.This particularly aggressive form of the disease accounts for about 70% of infant leukaemias, and 10% of adult acute leukaemias.Only half of children diagnosed with the disease survive for two years after receiving standard treatment.Double assaultA protein called Bmi1 was already known to play a key role in the survival and proliferation of various cancer stem cells.But the King’s team showed that targeting Bmi1 alone was not enough to eradicate the rogue stem cells, as had previously been thought. To do that, the scientists found that Bmi1 had to be targeted in harness with a second protein, Hoxa9.This double assault abolished the ability of MLL mutation to induce leukaemia.Researcher Professor Eric So said: “These findings take us a step forward in our understanding of how this devastating disease can return in patients after they have received the standard treatment.“Now we know that leukaemic stem cells in certain types of leukaemia, such as MLL, can survive and proliferate independently of the Bmi1 protein, we need to consider more carefully the future of stem cell therapy to treat the disease.“It’s not as easy as people originally thought it might be.”Professor So said the next step would be to pin down exactly how the two proteins help cancer cells to grow.Professor Peter Johnson, Cancer Research UK’s chief clinician, said: “Cancer stem cells appear to be more resistant to radiotherapy and chemotherapy than the other leukaemia cells, so understanding how they originate – and how we can kill them – will be a major step in being able to help even more people survive leukaemia in future.”Dr David Grant, scientific director of Leukaemia & Lymphoma Research, said: “It is now widely agreed that leukaemia stem cells are the true target for new or existing drugs if patients are to be cured.“This research is important in uncovering how leukaemia stem cells are controlled at the genetic level which in turn will guide new treatments to tackle this difficult problem.”BBC News Share HealthLifestyle Hopes raised of blocking return of leukaemia by: – June 4, 2011 Share Sharing is caring!center_img Share 15 Views   no discussions Tweetlast_img read more

first_imgLausanne: Experienced Australian lawyer and judge James Wood has been appointed as the chairman of the World Anti-Doping Agency (WADA) Compliance Review Committee. He has replaced Britain’s Jonathan Taylor.The 78-year-old’s appointment was made at an extraordinary WADA Executive Committee meeting — the first to be chaired by new WADA President Witold Banka — at the International Olympic Committee (IOC) headquarters on Thursday.New Zealand’s Ben Sandford was confirmed as chairman of the WADA Athlete Committee.WADA’s Executive Committee also confirmed the appointment of Singapore’s Ser Miang Ng, a member of the IOC Executive Board, as chairman of the Finance and Administration Committee.Miang Ng, who chairs the IOC’s Finance Commission, succeeds Association of Summer Olympic International Federations President Francesco Ricci Bitti. IANS Also Read: Hollywood actor Daniel Craig confirms his time as James Bond is endingAlso Watch: Ajmal Foundation distributes 10 Computers to Axom Sahitya Sabha in Guwahatilast_img read more